diabetic mice and teeth health

Today’s Top Stories in Diabetes News!

What diabetic mice can teach us about keeping teeth healthy

BY DANA GRAVES: Along with all the other consequences of poorly managed diabetes, patients who don’t or can’t control their sugars are more likely to lose their teeth because of severe periodontitis, an irreversible gum disease that attacks the tissues and bone around the teeth.

The connection has long been known. But exactly why it happens hasn’t been so well-understood. Now, a new study by University of Pennsylvania researchers that was supported by the National Institute of Dental and Craniofacial Research shows that unmanaged diabetes changes bacteria in the mouth so that microbes are more capable of causing disease. That means more inflammation of the gums and bone loss.

The findings on the oral microbiome, researchers hope, will help lead to better dental treatments for people with diabetes — and anyone with periodontitis. (read more)


Type 2 diabetes risk four times higher in women with polycystic ovary syndrome

BY ANA SANDOIU: Polycystic ovary syndrome is a widespread condition among women of reproductive age, and a new study suggests that it may also put these women at a significant risk of developing type 2 diabetes.

The research was carried out by Denmark-based scientists and the findings were published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

The Centers for Disease Control and Prevention (CDC) report that polycystic ovary syndrome (PCOS) is the leading cause of female infertility, with up to 5 million women in the United States affected by the condition.

Women with PCOS often have insulin resistance, which is a condition wherein the muscles, fat, and liver do not respond properly to the hormone, so the body keeps producing more of it. (read more)

Type 2 diabetes and antidepressant drug use: Is there a causal link?

BY SWETA GUPTA: There is a growing evidence linking antidepressant drug (AD) use with type 2 diabetes (T2D).1,2 Given the high prevalence of both diabetes and AD use in many countries, researchers at the ASST Fatebenefratelli-Sacco in Milan, Italy, and the University of Eastern Piedmont in Novara, Italy, set out to provide a comprehensive evaluation of the risk for diabetes associated with AD use in a systematic literature review of relevant studies in PubMed, PsychINFO, and International Pharmaceutical Abstracts. The updated meta-analysis, recently published in PLoS One, confirmed the association between AD use and the risk for T2D.3

Twenty studies, published between January 1, 2000, and December 31, 2016, evaluating the incidence of new-onset diabetes in patients treated with ADs compared with nonusers were included. (read more)