BY KELLY BASTONE: Sugar is everywhere. It’s in practically every food we eat, from candified yogurts to the breakfast cereal we wash down with a flavor-of-the-month Frappuccino. Though we know it’s not good for us in excess, it’s also so hard to resist. That’s because eating sugar lights up our brains’ dopamine receptors (the same ones that trigger drug addiction), making us feel fantastic—and eager for another hit. As runners, our sugar problem is even stickier, as we rely on gels and energy drinks (and sometimes just plain candy) to fuel and recover from workouts.
Sadly, running doesn’t make you immune from the detrimental health effects of eating too much refined sugar. The nearly 152 pounds of added sugar that each American consumes a year increases our risks of obesity, diabetes, heart disease, depression, and sleep disorders. That’s true whether you exercise or not. (read more)
BY BXINHUA: People suffering diabetes run two- to five-fold risks of heart failure if they have excess fat in the heart, which harms the cells’ essential ability to produce energy, a new study revealed.
Diabetes and obesity are often characterized with excess fat in the heart, which is the most energy-hungry organ in human body.
According to the study, conducted by researchers at the University of Iowa (UI) and published in the latest edition of journal Circulation Research, lipid overload in the heart causes numerous small, misshapen mitochondria that don’t produce energy as efficiently as normal mitochondria. (read more)
BY MELISSA HEALY: The newly resurgent field of gene therapy, which recently produced treatments for blood cancers and blindness, has taken a step toward fighting a scourge that is on the rise worldwide: diabetes.
In research reported last week in the journal Cell Stem Cell, scientists showed that a single infusion of a virus containing two handpicked genes restored normal blood sugar levels in mice with Type 1 diabetes.
Although the effects of the therapy faded after four months, prompting the mice to return to their diabetic state, the equivalent improvement in humans could last for several years, the researchers said.
Type 1 diabetes occurs when the immune system attacks the beta cells in the pancreas that make insulin, a hormone needed to metabolize the sugar in foods. In Type 2 diabetes, the pancreas can still make some insulin but the body isn’t able to use it properly. (read more)
Tandem Diabetes (TNDM) Reports Successful Completion of First Pilot Study Using t:slim X2 Insulin Pump
BY STREET INSIDER: Tandem Diabetes Care®, Inc. (NASDAQ: TNDM), a medical device company and manufacturer of the only touchscreen insulin pumps available in the United States, today reported the successful completion of the first pilot study using a hybrid closed loop system featuring its t:slim X2™ Insulin Pump with embedded algorithms from TypeZero Technologies and integration with Dexcom® G6 Continuous Glucose Monitoring (CGM). This pilot study was the first of three in the National Institute of Health (NIH)-funded International Diabetes Closed Loop (IDCL) Trial using the t:slim X2 Pump running the algorithm directly on the pump. The second study is now moving forward with enrollment at seven clinical sites and is anticipated to begin in the first quarter of 2018. The IDCL Trial is expected to conclude with a pivotal study in 2018, and Tandem plans to use this data in a PMA submission to the U.S. Food and Drug Administration. (read more)
BY CNN WIRE: If you’re a fan of the “fat-burning” keto diet, you’ll be fired up about its ranking in the 2018 list of best diets from US News and World Report: It’s tied for last, along with the relatively unknown Dukan diet.
Both stress eating a ton of protein and minimal carbs, putting the dieter into “ketosis,” when the body breaks down both ingested and stored body fat into ketones, which it uses as energy. People on such diets often deal with fatigue and light-headedness as they adjust to a lack of carbohydrates.
Though the experts on the US News and World Report panel that created the list said eating that way isn’t harmful short-term, they ranked the diets poorly on long-term weight loss success, ease of use and overall impact on health. (read more)