BY ROBERT PREIDT: Occasional fasting may help control type 2 diabetes, a small Canadian study suggests.
“The use of a therapeutic fasting regimen for treatment of [type 2 diabetes] is virtually unheard of,” said Dr. Jason Fung, of Scarborough Hospital, in Ontario, and colleagues.
But this trial showed that 24-hour fasting regimens can significantly reverse or eliminate the need for diabetic medication, the study authors said.
Three men, aged 40 to 67, were taking various drugs and daily insulin injections to control their diabetes. They also had high blood pressure and high cholesterol.
After a six-hour training seminar, two of the men fasted on alternate days for a full 24 hours, while the third fasted three days a week. (read more)
BY THOMAS H. DAVENPORT: … But both traditional and precision medicine confront a “last mile problem” involving patient behavior change: even the most appropriate medical treatment will be effective only if the patient follows through on it. The cost of medication non-adherence is conservatively estimated at more than $250 billion a year in the US, and the majority of hospital readmissions after surgery are due to non-adherence to discharge protocols. (read more)
BY NIDDK: New results from the Beta Cell Restoration through Fat Mitigation study (BetaFat), part of the Restoring Insulin Secretion (RISE) study, show that people with prediabetes or new-onset type 2 diabetes who had gastric banding, a type of bariatric surgery for weight loss, had similar stabilization of their disease to those who took metformin alone.
The study found that after two years, people in the gastric banding group lost significantly more weight, an average of 23 pounds, compared to four pounds in the metformin group. In addition, the two treatment groups showed similar improvements in insulin sensitivity and relatively stable function of insulin-producing cells, with small improvements in blood glucose levels. (read more)
BY BECKY McCALL: Type 2 diabetes may start up to 20 years before diagnosis with a slow build-up of metabolic changes including alterations in fasting plasma glucose and insulin sensitivity, shows a study that explored the timeline of progression to diabetes by comparing data from people who did and did not go on to develop the disease.
Hiroyuki Sagesaka, MD, from Aizawa Hospital in Matsumoto, Japan, led the research, along with Mitsuhisa Komatsu, MD, PhD, from Shinshu University Graduate School of Medicine, Matsumoto, Japan, and colleagues. Komatsu presented the results here at the European Association for the Study of Diabetes (EASD) 2018 Annual Meeting.(read more)
BY FRANK J. CONNOR: Diabetes has been associated with significantly elevated odds of having arthritis and musculoskeletal pain, according to research presented at the 54th annual meeting of the European Association for the Study of Diabetes in Berlin, Germany. The findings indicated that osteoarthritis was the most common form of arthritis in patients with diabetes but that rheumatoid arthritis had the most pronounced association with diabetes.
Data from previous studies have associated musculoskeletal pain with type 2 diabetes (T2D). Researchers in this study aimed to investigate the association between diabetes and arthritis, particularly osteoarthritis, osteoporosis, and rheumatoid arthritis. (read more)