BY JACK WOODFIELD: A major grant has been awarded to a US researcher who will further investigate stem cell therapies for type 1 diabetes treatments.
Xiaojun “Lance” Lian, assistant professor of biomedical engineering at Penn State University, is one of three recipients of the College of Engineering’s ENGineering for Innovation &Entrepreneurship (ENGINE) grant.
Now in its fifth year, ENGINE grants provide financial support to early-stage research results through a proof-of-concept phase. (read more)
BY MARTY STEMPNIAK: Using a more simplified medication regimen and tailoring glycemic targets for older adults with both diabetes and cognitive impairment are among new guidelines for providers to address the disease.
The Endocrine Society recently issued these new practice guidelines to aid in treating diabetes, which currently affects about 33% of seniors in the U.S. Other recommendations include targeting blood pressure levels of 140/90 mmHg to decrease the risk of developing cardiovascular problems, and administering annual eye exams to detect retinal disease. (read more)
BY MEDICAL XPRESS: Researchers at Karolinska Institutet in Sweden have identified a mechanism that can explain the impaired wound healing in diabetes which can lead to diabetic foot ulcers. The study is published in the scientific journal Proceedings of the National Academy of Sciences. In diabetic mice, wound healing improved when the identified signalling pathway was blocked.
Diabetic foot ulcerations are a common complication of diabetes that constitute a major medical, social and economic issue. The lifetime risk of a person with type 1 or type 2 diabetes developing a foot ulcer is around fifteen percent. The treatment options are currently limited due to a poor understanding of the pathogenic mechanisms. (read more)
BY dLIFE: Patients on medication for Type 2 diabetes may be keeping Alzheimer’s disease away.
University of Southern California Dornsife psychologists found that those patients with untreated diabetes developed signs of Alzheimer’s disease 1.6 times faster than people who did not have diabetes.
BY SERENA GORDON: A commonly used diabetes test may not spot the disease as well as an older test does, a new study suggests.
The researchers said the newer test — called hemoglobin A1C — didn’t catch three-quarters of the diabetes diagnoses found by the older test — called an oral glucose tolerance test.
“Diabetes is a global epidemic. Since the incorporation of A1C [as a test for diagnosis] in 2010, it’s been relied on more and more for its convenience because patients don’t have to fast. But it’s not a perfect test,” said study author Dr. Maria Mercedes Chang Villacreses. She is an endocrinology fellow at the City of Hope National Medical Center in Los Angeles. (read more)