insulin aspart, FDA, children, Fiasp

FDA Approves Insulin Aspart for Use in Children

The U.S. FDA approved Novo Nordisk’s Fiasp fast-acting insulin aspart for use in children. Fiasp is a mealtime (bolus) insulin that does not have a pre-meal dosing recommendation. 

Fiasp was first approved for use in adults in 2017. It can be used as injections, through an insulin pump, or via intravenous infusion under the supervision of a doctor. 

The benefits of insulin aspart for children

The approval of Fiasp in children is especially beneficial since children’s eating patterns can be unpredictable. Since you can administer this fast-acting insulin before a meal or within 20 minutes after starting the meal, it will be easier for children with type 1 and their parents to keep blood sugar spikes under control.


About Fiasp

The insulin aspart treatment starts working within 2 minutes. It reaches maximum effect between 1 and 3 hours after injection, and lasts between 3 and 5 hours. Care should be taken to rotate injection sites. 

Todd Hobbs, VP and North America Chief Medical Officer at Novo Nordisk, said: “As a parent of a son living with Type 1 diabetes, I know first-hand how tough it can be to address the inevitable blood sugar spikes around mealtimes. Children can be unpredictable and having the option of fast-acting insulin that doesn’t require pre-meal dosing like Fiasp is a welcome development for the diabetes community.”  

Type 1 diabetes

Type 1 diabetes is usually diagnosed in childhood, with nearly 18,000 new cases of type 1 each year. Type 1 is an autoimmune disorder in which the pancreas creates little to no insulin to help the body convert sugar into energy. When this happens, sugar builds up in the bloodstream and can damage blood vessels throughout the body. Keeping blood sugar within a healthy range is crucial for type 1 diabetes, and people with type 1 will have to take insulin through injections or a pump.


Bolus and basal insulin

Before eating a meal, a person with diabetes injects bolus, or mealtime, insulin. This works to counteract blood sugar highs brought on by eating. The amount of insulin can be adjusted depending on how many carbs are consumed in the meal. Bolus insulin will be rapid-acting or short-acting. Examples of bolus insulin include aspart, lispro, and glulisine.

A person with type 1 will also take basal insulin one or twice a day in order to regulate blood sugar levels. Basal insulin is longer-acting. Examples of basal insulin include glargine, detemir, and degludec.